Tuesday, April 30, 2013

VW brand bears brunt of crisis as first-quarter profit halves

BERLIN (Reuters) - First-quarter profit at Volkswagen's core brand almost halved, Europe's biggest carmaker said on Monday, as manufacturers battle the region's protracted slump in demand with ever deeper discounts.

Operating profit at the VW brand, which accounts for over half the German group's 46.6 billion-euro ($60.7 billion) sales, plunged to 590 million euros, VW said, giving details on a drop in quarterly group earnings announced last week.

The VW brand's profit margin tumbled to 2.4 percent from 4.1 percent in the first three months of 2012.

"The current environment is definitely a tough challenge for the entire industry," Chief Executive Martin Winterkorn said in a statement.

VW-brand deliveries, including VW's all-time best-selling Golf hatchback, fell in March for the first time in over three years.

Still, the company said last week it would stand by targets announced on March 14 to match the 2012 record operating profit of 11.5 billion euros and to push sales and deliveries to new record levels.

Wolfsburg-based VW is pinning its hopes for growing sales volumes on about 60 new models this year including facelifts and overhauls as well as the new Golf, launched in November.

One VW dealer told Reuters the multi-brand group has been pushing sales of models like the Golf or the Tiguan compact SUV since February with retail sales incentives of as much as 1,800 euros per vehicle under a special discount program slated to run through June 30.

Depending on VW's budget, the program could be extended by another 3 months, the dealer said, declining to be identified as the sales policy is confidential.

"The VW group is not completely immune to the intense competition and the impact this is having on business," CEO Winterkorn said.

Underlying profit at the Audi luxury brand declined 7.3 percent to 1.31 billion euros, VW said.

The loss at Spanish division Seat widened to 46 million euros from 29 million euros a year earlier, underscoring the need for action as VW plans to swap the brand's CEO on May 1.

(Reporting by Andreas Cremer; Editing by Ludwig Burger and Mark Potter)

Source: http://news.yahoo.com/vw-brand-bears-brunt-crisis-first-quarter-profit-103511485.html

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Global stocks, euro rise on Italy government; S&P 500 nears record

By Caroline Valetkevitch

NEW YORK (Reuters) - World stock indexes and the euro advanced on Monday as the formation of a new government in Italy eased uncertainty about the political future of the country, the third-largest economy in the euro zone, while tame inflation data drove down U.S. Treasury yields.

U.S. stocks jumped, also buoyed by stronger-than-expected U.S. housing data. The S&P 500 extended recent gains and was on track for a record closing high. The index is up 11.9 percent for the year so far.

"Wall Street appears primed for another assault at record highs," said Andrew Wilkinson, chief economic strategist at Miller Tabak & Co in New York.

U.S. price data showed inflation remained quiet, suggesting the Federal Reserve, which will begin a two-day policy meeting on Tuesday, will not be ending its accommodative monetary stance any time soon.

Recent signs of weak U.S. growth had raised expectations the Fed will keep its pace of bond buying unchanged at $85 billion a month at its meeting this week, while the European Central Bank is widely expected to announce an interest rate cut when it meets on Thursday.

Investors welcomed the formation of a broad coalition government in Italy under new Prime Minister Enrico Letta, two months after inconclusive general elections, though investors remain cautious over how long the new growth-focused government will survive.

The resolution of Italy's political stalemate helped bring its five- and 10-year borrowing costs down to their lowest level since October 2010 at a bond sale on Monday, while yields on 10-year debt in the secondary market fell 13 basis points to 3.93 percent.

"Italian sovereign debt is benefiting from the twin effects of central bank liquidity support and political stability of sorts," said Nicholas Spiro, managing director of London-based consultancy Spiro Sovereign Strategy.

MSCI's world equity index <.miwd00000pus> was up 0.8 percent, while the broad FTSE Eurofirst 300 index <.fteu3> of top European shares provisionally closed up 0.5 percent, led higher by Milan's FTSE MIB <.ftmib>, which rose 2.2 percent.

The Dow Jones industrial average <.dji> was up 121.68 points, or 0.83 percent, at 14,834.23. The Standard & Poor's 500 Index <.spx> was up 13.74 points, or 0.87 percent, at 1,595.98. The Nasdaq Composite Index <.ixic> was up 34.42 points, or 1.05 percent, at 3,313.68.

The Fed's stimulus measures have helped U.S. stocks rally for much of this year.

The euro rose 0.5 percent to $1.3095, with hedge funds cited among key buyers. The euro's session peak of $1.3115, the highest since April 19, was reached midway through the London session.

Some analysts say the euro could weaken should the ECB cut its main interest rate by 25 basis points, from 0.75 percent currently, when it meets on Thursday; a rate cut would erode the euro's interest rate advantage over the dollar and yen.

"The euro would likely weaken somewhat on that, but the overall move will be muted," said John Doyle, currency strategist at Tempus Consulting in Washington, D.C. "The expectation is starting to get priced in."

A Reuters poll of 76 economists last Thursday showed only a narrow majority of 43 expected a 25-basis-point cut at this week's ECB policy meeting, which would take the bank's refinancing rate to a record low of 0.5 percent.

Inflation, as reflected in the personal consumption expenditure price index, rose just 1 percent over the 12 months through March, the smallest gain since October 2009 and a slowdown from the 1.3 percent logged in the period through February.

Benchmark U.S. 10-year Treasuries were unchanged, with the yield at 1.665 percent.

U.S. data also showed that contracts to purchase previously owned U.S. homes rose in March as the housing market continued to pick up pace this year.

A weaker dollar helped drive gains in both U.S. crude oil prices and gold.

U.S. light crude was up $1.34 at $94.34. Brent crude was up 59 cents to $103.75 a barrel, after making its biggest weekly gain since November last week.

Spot gold rose 1 percent to a session high of $1,477.70 an ounce but then pared the gains to trade at $1,468.19 an ounce.

(Additional reporting by Wanfeng Zhou and Angela Moon in New York; Editing by Dan Grebler and Leslie Adler)

Source: http://news.yahoo.com/asian-shares-edge-markets-cautious-ahead-events-packed-010340344.html

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Monday, April 29, 2013

Discuss HR: 5 Reasons Why You Should Be Blogging For Your HR ...

Discuss HR: 5 Reasons Why You Should Be Blogging For Your HR Business

5 Reasons Why You Should Be Blogging For Your HR Business


Today is the first post in our guest blogger week and we welcome Ruth Hinds who looks at why you should write a blog.? (Ed Scrivener) 5 Reasons Why You Should Be Blogging For Your HR Business If you?re serious about growing your HR business and building a steady stream of enquiries and potential clients, you?ve probably heard that blogging could be a great way to take things to the next level. With statistics showing that 57% of businesses have acquired a new customer through their blog, rising to 92% for those which blog regularly (HubSpot State of Inbound Marketing, 2012), it?s clear that there?s massive potential for businesses that are getting it right. Here are five reasons why you should be blogging for your HR business. It?s a great way to boost your search engine rankings Search engines such as Google love fresh content, and writing a regular blog post on your website is a sure-fire way to make sure that your business appears in the results when people are searching for businesses just like yours. At the moment, your site might rank on the tenth page when users are looking for what you offer. It?s unlikely that anyone will look beyond the first page of results, so you?re essentially just giving away custom to your competitors. A consistent approach to blogging will boost your rankings, and this has an obvious positive impact on the number of enquiries and new clients that you acquire. Blog content can be repurposed for maximum exposure Once your blog post is written, it can be used over and over again to market your business. Of course, you?ll initially share it with your social media followers and include it in your email newsletter. You might send it directly to clients that you think it would benefit. Beyond the obvious though, the only limit is your creativity. You could record the content as a webinar, or turn several posts into an e-book. When you have a robust content strategy in place, it also guides the rest of your marketing materials for the rest of the month. Just one post can guide your social media updates and other collateral, giving you inspiration and one less thing to worry about. You?ll gain a reputation as a thought leader in your field If you?re creating top notch content on a regular basis, people will start to sit up and take notice. They?ll recognise just how knowledgeable you are in your area of expertise, and will be convinced that when they need services just like yours, they should turn to you. Don?t worry about ?giving away your knowledge for free?. Positioning yourself as a thought leader in your field with result in stronger relationships and a feeling of trust amongst your followers, which will only have a positive affect on your bottom line. It gives potential customers a reason to revisit your website So many HR consultants set up a website for their business but then never update their content. The result of this is that potential customers visit once, but then forget all about it. A site that isn?t visited regularly and provides a useful resource for visitors is essentially a waste of money. When you blog on a regular basis, you?re giving people a reason to return and see what you?re all about. Strong blog content, coupled with compelling website copy that inspires readers to take action is the secret ingredient for making your site work for you. It?s a cost effective marketing tool? Marketing your business can cost a small fortune, especially if you?re using traditional methods such as magazine advertising. One of the beauties of blogging is that it?s remarkably cost effective. Yes, you?ll have to invest some time in coming up with content ideas and crafting engaging posts, but this process comes much easier with practice. If you struggle with this type of writing or you just don?t have the time, you could even use the services of a copywriter. Making a small investment to bring in the professionals will mean that you?re better placed for success from the start. You should always make sure that you?re using a writer with experience in your field and a good grasp of what your business does. As you can see, blogging for your HR business can have many benefits when it comes to attracting new clients and boosting your brand awareness. To get ahead of the crowd and gain a competitive edge against others in your sector, it?s well worth considering whether it should be in your marketing mix. Are you thinking about building a blog? What?s stopping you from getting started? Ruth Hinds is a former HR professional with experience at business partner and management level in the public and private sector. She is now the director of Red North Media, a copywriting and business blogging consultancy that focuses on solutions for HR and recruitment businesses. Discuss HR is the HR blog written by members of Human Resources UK, the 10,000 member strong LinkedIn group dedicated to the HR professionals in the UK.? Discuss HR is published twice weekly and looks to take an insightful, informative and sometimes irreverent view on the world of HR ? all with the purpose of generating a discussion.

Source: http://discusshr.blogspot.com/2013/04/5-reasons-why-you-should-be-blogging.html

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JPMorgan co-COO Bisignano leaves to run First Data

NEW YORK (AP) ? JPMorgan Chase & Co. said Sunday that one of its co-chief operating officers is leaving the company, marking the latest high-profile departure since the bank's massive trading loss last year.

Frank Bisignano will become CEO of payment processor First Data Corp. on Monday. Matt Zames, who was co-chief operating officer with Bisignano, will become the sole COO of JPMorgan Chase effective immediately.

First Data said Bisignano, 53, succeeds Ed Labry, who has been interim CEO and president of Retail and Alliance Services since Jan. 28. Labry will continue as president of Retail and Alliance Services.

Bisignano and Zames were named co-chief operating officers in a management reshuffle in July after JPMorgan Chase revealed a trading loss of about $6 billion. The massive loss became a focus of the risky bets taken at large banks and oversight of traders who make those bets. It also prompted congressional hearings, as well as investigations by international regulators.

Others called for the resignation of CEO Jamie Dimon, who initially called the trade a "tempest in a teapot." Dimon later backtracked and apologized several times for the mischaracterization after the scope of the loss was revealed.

The Wall Street Journal first reported that Bisignano would be the ninth executive in the past year and a half to leave Dimon's operating committee of key decision makers.

Dimon and Bisignano have known each other since the 1980s, according to the Journal, and worked together at Citibank.

Before he was named co-chief operating officer this summer, Zames had taken over as chief investment officer for Ina Drew, who resigned in the days after the big trading loss was revealed.

JPMorgan also said Sunday that Paul Compton will become chief administrative officer. He is currently co-chief administrative officer of the Corporate & Investment Bank and deputy head of operations for JPMorgan Chase.

Louis Rauchenberger, who shares Compton's current role, will become sole chief administrative officer of the Corporate and Investment Bank.

Source: http://news.yahoo.com/jpmorgan-co-coo-bisignano-leaves-run-first-data-201958581.html

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Italy progress lifts Wall Street, S&P near record

By Ryan Vlastelica

NEW YORK (Reuters) - Stocks rose on Monday, extending a recent rally as Italy formed a government and relieved a two-month-long overhang of geopolitical uncertainty from the market.

In addition, better-than-expected housing data boosted market optimism and put the S&P 500 on track to set a record close after rising for six of the past seven sessions.

Wall Street followed European stocks higher as Italy's new Prime Minister Enrico Letta's focus on growth and away from austerity in his inaugural speech lifted hopes for further stimulus from the European Central Bank.

"After the election there was a lot of uncertainty about whether Italy could form a government, so now there is not only a great deal of relief over that, but also expectations for additional monetary policies from the ECB," said Alec Young, global equity strategist at S&P Equity Research in New York.

Policymakers of the ECB and the U.S. Federal Reserve will meet separately this week, and the Fed is expected to maintain its stimulus. Data on Monday showing muted inflation continued to give the Fed room for accommodative measures.

Also lifting markets was Apple Inc , which jumped 3.5 percent to $431.53 after taking initial steps for what would be its first debt sale, which is set to be one of the most anticipated bond sales of the year. Technology stocks <.splrct> rose 1.7 percent the best-performing sector on the day.

A report showed contracts to buy previously owned homes rose last month to their highest level since April 2010, showing underlying strength in the housing market recovery, even though the pace of sales growth has cooled in recent months.

The Dow Jones industrial average <.dji> was up 126.17 points, or 0.86 percent, at 14,838.72. The Standard & Poor's 500 Index <.spx> was up 13.93 points, or 0.88 percent, at 1,596.17. The Nasdaq Composite Index <.ixic> was up 34.17 points, or 1.04 percent, at 3,313.43.

The S&P 500 is about a point away from 1,597.35, its all-time intraday high, which it hit earlier this month. If the index closes above 1,593.37, that will mark a new all-time closing high.

"The market's trend continues to be higher, but it is still attractive at these valuations," said Young, who has a 12-month target of 1,670 for the S&P.

Moody's Corp was the S&P 500's top percentage gainer, jumping 9.4 percent to $60.29 after the company settled a lawsuit alleging that it had misled investors about the safety of risky debt vehicles it had rated.

McGraw-Hill Cos , whose Standard & Poor's unit said it settled similar suits, rose 3.2 percent to $53.64.

Roper Industries Inc fell 3.5 percent to $118.96 after reporting first-quarter revenue that missed expectations, though it raised its full-year profit outlook.

Of the 274 companies in the S&P 500 that have reported earnings to date for current season, 69 percent have beat analysts' expectations and 43.2 percent have reported revenue above expectations.

The second half of the earnings season may not be as strong as the first one, data showed.

(Editing by Nick Zieminski)

Source: http://news.yahoo.com/stock-futures-higher-ahead-data-corporate-results-115148731.html

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&#39;Must see video&#39; : 10 simple, clever tips for computer, web ...

by Will Corry on April 27, 2013 in Advertising, Apps, Apps & Software, Businesswoman, Events & Awards, FaceBook, Gadgets, Google, iPhone, Lead story, LinkedIn, Media, Metrics, Mobile, Mobile Marketing, Pinterest, Retail, Small Business, Startups, Twitter, Videos, Websites

Tech columnist David Pogue shares 10 simple, clever tips for computer, web, smartphone and camera users. And yes, you may know a few of these already ? but there?s probably at least one you don?t.

The ?must see? video

David Pogue is the personal technology columnist for the New York Times and a tech correspondent for CBS News. He?s also one of the world?s bestselling how-to authors, with titles in the For Dummies series and his own line of ?Missing Manual? books.?Full bio ?

Print article

Source: http://www.themarketingblog.co.uk/2013/04/must-see-video-10-simple-clever-tips-for-computer-web-smartphone-and-camera-users/?utm_source=rss&utm_medium=rss&utm_campaign=must-see-video-10-simple-clever-tips-for-computer-web-smartphone-and-camera-users

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Sunday, April 28, 2013

Italy's Saccomanni moves from central banker to economy minister

By Gavin Jones

ROME (Reuters) - Italy's new Economy Minister Fabrizio Saccomanni is a 70-year-old central banker virtually unknown to the general public, who should reassure financial markets and the rest of Europe that the country will not stray from fiscal orthodoxy.

He has spent most of the last 46 years at the Bank of Italy, where he is deputy governor, having been passed over for the top job when Mario Draghi left in 2011 to head the European Central Bank.

Few can doubt Saccomanni's knowledge of economics and finance, but without any party affiliation he may lack the political clout to push through unpopular policies and risks being caught in the crossfire of cabinet infighting.

Draghi pushed for his deputy to replace him when he left the Bank of Italy but Saccomanni was opposed by Silvio Berlusconi's center-right government and compromise candidate Ignazio Visco leapfrogged him in the bank's hierarchy to become governor.

That was not the first time Saccomanni missed out. In 1998 he was expected to be Italy's first member of the ECB's six-member executive board but lost out to Tommaso Padoa-Schioppa, who was more favored by Romano Prodi's center-left government.

Reserved but amiable, with a dry sense of humor, Saccomanni continues a tradition of technocrats who have made the move from the Bank of Italy to the economy ministry, the most recent examples being Padoa-Schioppa and Carlo Azeglio Ciampi.

He had to overcome the resistance of Berlusconi, a key stakeholder in Prime Minister Enrico Letta's left-right coalition, who said on Friday that Saccomanni would be an unacceptable appointment.

"We've had enough of technocrats, we have been through a government that created a disaster because of its excessive fiscal rigor," he said, in reference to Mario Monti's outgoing technocrat administration.

RECESSION

Saccomanni publicly backed Monti's austerity policies several times, abandoning his usual reserve to take on a role of convincing the press and investors of Italy's creditworthiness at the height of the euro zone debt crisis in 2011 and 2012.

However the central bank's forecasts proved far too optimistic on Italy's growth prospects as the country sank into its longest recession for 20 years.

As economy minister, Saccomanni's primary task will be to breathe life into the euro zone's third largest economy with structural reforms and growth-boosting measures without allowing public finances to go off the rails.

One thing the center-right and center-left components in the broad coalition most strongly agree on is that Italy must try to re-negotiate its fiscal targets with Brussels and win more leeway to stimulate the ailing economy.

With his economic experience, international credibility and fluent English, Saccomanni will be well placed to present Italy's case.

Despite his low public profile he has been well known to the international financial elite for decades. He sits on the board of the Bank for International Settlements in Basel and was one of the behind-the-scenes negotiators who prepared Italy for European Monetary Union in the 1990s.

A native of Rome, he studied economics at Milan's Bocconi University and later at Princeton University in the United States and joined the banking supervision department of the Bank of Italy in 1967.

He has been at the central bank ever since, excluding stints on secondment to the International Monetary Fund from 1970 to 1975 and as deputy president of the London-based European Bank for Re-construction and Development from 2003-2006.

Saccomanni is married with no children.

(Editing by Stephen Powell)

Source: http://news.yahoo.com/italys-saccomanni-moves-central-banker-economy-minister-185526638.html

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&#39;Gayle On The Go&#39; For Saturday April 27 | KTLA 5

KTLA5 reporter Gayle Anderson gives us a preview of some events taking place this weekend around Los Angeles.

Saturday @ 7 a.m.
11th Annual Donate Life Run/Walk Family Festival
Cal State Fullerton
Intramural Field
800 North State College Boulevard
Fullerton
www.donateliferunwalk.org

?Enjoy the Saturday morning sun with a fun 5K walk-run and 1K fitness run organized by Donate Life. This is an opportunity to meet and greet the community and learn about organ and tissue donation program benefitting the One Legacy Foundation.

?Saturday @ 6:30 a.m.
17th Annual Shelter?s Right Hand 5K Fitness Walk
Central Park?
Historic Uptown Whittier
www.sheltersrighthand.org

??

Get a ?Lose Five with Five? workout at the Shelter?s Right Hand 17th Annual 5k Fitness Walk in historic Uptown Whittier?s Central Park. The exercise benefits the Women?s and Children?s Crisis Shelter.

?

Saturday @ 6 a.m.
AbilityFirst Stroll & Roll
Universal Studios Backlot
100 Universal City
Universal City
www.abilityfirststrollandroll.kintera.org?

?The AbilityFirst Stroll & Roll is a fundraiser to support programs for children and adults with physical and developmental disabilities. ?Join the fun and adventure and walking for 2-and-a-half miles on the Backlot of Universal Studios.

Saturday @ 9 a.m.
Health Kids Day
Torrance-South Bay YMCA
2900 West Sepulveda Boulevard
Torrance
310 325 5885

?

It?s ?Healthy Kids Day? at the Torrance ? South YMCA. It?s a day to inspire families to help kids stay physically and intellectually active throughout the summer.? Saturday at the Y will be filled with active play, educational activities, performances and prizes.

?
Free!
Saturday @ 10:30 a.m.
Santa Monica Mountains Science Fest Paramount Ranch
2903 Cornell Road
Agoura Hills
805 370 2301
www.nps.gov/samo/sciencefestical.htm
?

This is for inquiring minds of all ages! Become a citizen scientist; learn how to track mountain lions, bobcats, and island foxes; get to know the local wildlife; and discover the mysteries of your neighborhood national parks, at the 4th annual Science Festival. This free event is sponsored by the National Park Service in partnership with the Natural History Museum of Los Angeles County, the Children?s Nature Institute, Santa Monica Mountains Fund, UCLA LaKretz Center for CA Conservation Science, and NatureBridge.

Saturday
Los Angeles Children?s Film Festival
Aero Theatre
1328 Montana Avenue
Santa Monica
www.americancinematheque.com

?

Looking for something fun to do with your kids? Want to share a movie with them but dread walking into most feature length movies? Look no further. The Los Angeles Children?s Film Festival offers animated and live action shorts and films from around the world for everyone ages 3-18.

?
Saturday @ 11a.m.
45th Anniversary Bug In Celebration

Heroes Bar & Grill
125 West Santa Fe Ave

Fullerton
714 738 4356

www.BugIn.com

?

It?s Volkswagen lovers weekend. Celebrate the 45th anniversary of Bug-In with a get-together in Fullerton. Volkswagen owners? are preparing for some rubbing and racing Sunday on the drag strip at the Irwindale Event Center.

?Saturday @ 10a.m.
Gems of the Medici
The Bowers Museum
2002 North Main Street
Santa Ana
71 567 3600

www.bowers.org

??

Gems of the Medici highlights some of the oldest and most unique pieces of the Medici collections. The Medici Family was an Italian financial and political dynasty during the late 14th century. They made their money in textiles.


Free!
Saturday @ 4 p.m.
Black Talkies on Parade Film Screening??
7th Annual Leimert Park Village Book Fair
301 202 1647
www.ClaytonMuseum.org

??

Saturday?s 7th Annual Leimert Park Village Book Fair has a bonus. The Mame Clayton Museum?s ?Black Talkies On Parade? Film series is screening Saturday afternoon the documentary, LEIMERT PARK: THE STORY OF A VILLAGE IN SOUTH LOS ANGELES. The film explores the neighborhood, its people as well as its art, music, and poetry scenes. After the screening, the filmmakers will have a panel discussion about the film and the dynamic history and culture of Leimert Park.? ?

?

?Saturday @ 11 a.m.
Garden Tour
Dominguez Rancho Adobe Museum
18127 South Alameda Street
Rancho Dominguez
310 603 0088
dominguezrancho.org

Saturday @ 9am
1st Annual Craft Faire
American Legion Auxiliary
Hawthorne 314??
14124 South Prairie Avenue
Hawthorne
310 675 1313?

Support our veterans at the first annual craft faire at the American Legion Auxiliary in Hawthorne. Proceeds from the sale of ?homemade jams, brownies, clothing, handmade jewelry, and more benefit veterans programs.

?

Saturday @ 7 a.m.
Women?s Health Forum
Los Angeles Convention Center
1201 South Figueroa Street
Los Angeles
213 741 1151
www.kjlhradio.com/kjlh-womens-health-forum?

Healthy is the new wealthy at the 13th Annual KJLH Women?s Health Forum. The free event offers free health screenings, exercise classes, breakout sessions, a holistic health wellness village, healthy food samples, free massages, prize giveaways and a vendor area. Oh! This is not just for women! Men can visit the ?Man Cave,? a 5,720 square foot environment JUST FOR MEN. The Man Cave will offer a variety of health screenings, such as prostrate screenings, STD screenings, HIV/AIDS testing, and BMI, diabetes, blood pressure, and lung function screenings.

?Saturday @ 9:50am
Day Out with Thomas
Thomas the Tank Engine & Friends Fillmore & Western Railway?
Fillmore Central Park
250 Central Avenue
Fillmore
866 468 7630
www.ticketweb.com

?Spend the weekend with Thomas the Tank Engine and Friends at the world famous Fillmore and Western Railway Company, known as ?Home of the Movie Trains.? Take a ride with classic storybook engine.

?Saturday @ 7pm
Race to Heal Hunger
Eurocar Showroom
2920 Red Hill Avenue
Costa Mesa
Benefitting the Orange County Food Bank
714 897 6670 x 5314
www.ocfoodbank.org?

In an effort to raise much needed funds and to bring awareness to the growing issue of hunger in Orange County, there the Race to Heal Hunger at the Eurocar Showroom. The special evening includes delicious delectables, live entertainment, benefitting the Orange County Food Bank.

?Saturday @ 9am
The Flower Fields
5704 Paseo Del Norte
Carlsbad
760 431 0352
www.theflowerfields.com
??

?And, time is running out to see the Flower Fields of Carlsbad is full bloom. These spectacular colors on the rolling hills of North San Diego County will only last through Mother?s Day weekend. The nearly fifty acres of Ranunculus flowers are in bloom will be gone until next spring.

?

Source: http://ktla.com/2013/04/27/gayle-on-the-go-for-saturday-april-27/

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Saturday, April 27, 2013

Congress approves bill to end delays in flights

WASHINGTON (AP) ? Congress hurried to approve legislation Friday that will end the furloughs of air traffic controllers that have delayed hundreds of flights daily, infuriating travelers and causing political headaches for lawmakers.

The House approved the measure on a 361-41 vote, a day after the Senate agreed to the bill. Friday's vote came as lawmakers prepared to leave town for a weeklong spring recess, a break that would have been less pleasant if they were confronted by constituents upset over travel delays.

Republicans accused the Obama administration of purposely furloughing controllers to pressure Congress to replace $85 billion in across-the-board spending cuts ? known as the sequester ? that took effect last month at government agencies.

"The administration has played shameful politics with the sequester at the cost of hard-working American families," said Rep. Tom Latham, R-Iowa.

The White House and Democrats have argued that by law, the administration has little room to decide where the cuts fall. They want Congress to work on legislation lifting all of the cuts, which lawmakers noted have also caused reductions in Head Start preschool programs, benefits for the long-term unemployed and medical research.

White House press secretary Jay Carney said the president would sign the new bill, but he added, "The problem is this is just a Band-Aid solution."

During House debate, House Minority Leader Nancy Pelosi, D-Calif., had a similar complaint.

"How can we sit there and say, 'Four million Meals on Wheels for seniors, gone, but that's not important. Over 70,000 children off Head Start, but that's not important," Pelosi said.

The Federal Aviation Administration has furloughed the controllers as part of the government-wide reductions. The bill would let the FAA use up to $253 million from airport improvement and other accounts to end the furloughs through the Sept. 30 end of the federal fiscal year.

In addition to restoring full staffing by controllers, the available funds can be used for other FAA operations, including preventing the closure of small airport towers around the country. The FAA had said it would shut the facilities to meet its share of the spending cuts.

The FAA said there had been at least 863 flights delayed on Wednesday "attributable to staffing reductions resulting from the furlough."

Administration officials participated in the negotiations that led to the deal and evidently registered no objections.

Sen. Susan Collins, R-Maine, a key participant in the talks, said the legislation would "prevent what otherwise would have been intolerable delays in the air travel system, inconveniencing travelers and hurting the economy."

Senate approval Thursday night followed several hours of pressure-filled, closed-door negotiations, and came after most senators had departed the Capitol on the assumption that the talks had fallen short.

For the White House and Senate Democrats, the discussions on legislation relating to one relatively small slice of the $85 billion in spending cuts marked a shift in position in a long-running struggle with Republicans over budget issues. Similarly, the turn of events marked at least modest vindication of a decision by the House GOP last winter to finesse some budget struggles in order to focus public attention on the across-the-board cuts in hopes they would gain leverage over President Barack Obama.

The Professional Aviation Safety Specialists, a union that represents FAA employees, reported a number of incidents it said were due to the furloughs.

In one case, it said several flights headed for Long Island MacArthur Airport in New York were diverted on Wednesday when a piece of equipment failed. "While the policy for this equipment is immediate restoral, due to sequestration and furloughs it was changed to next-day restoral," the union said.

The airlines, too, had pressed Congress to restore the FAA to full staffing.

In an interview Wednesday, Robert Isom, chief operations officer of US Airways, said, "In the airline business, you try to eliminate uncertainty. Some factors you can't control, like weather. It (the FAA issue) is worse than the weather."

In a shift, first the White House and then senior Democratic lawmakers signaled a willingness in the past two days to support legislation that alleviates the budget crunch at the FAA, while leaving the balance of the $85 billion to remain in effect.

Obama favors a comprehensive agreement that replaces the entire $85 billion in across-the-board cuts as part of a broader deficit-reduction deal that includes higher taxes and spending cuts.

Officials estimate it would cost slightly more than $200 million to restore air traffic controllers to full staffing, and an additional $50 million to keep open smaller air traffic towers around the country that the FAA has proposed closing.

___

Associated Press writers Joan Lowy, Henry C. Jackson and Alan Fram in Washington and David Koenig in Dallas contributed to this report.

Source: http://news.yahoo.com/congress-approves-bill-end-delays-flights-185034115.html

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Samsung to block access to app store in Iran

TEHRAN, Iran (AP) ? Iranian users of Samsung mobile applications said Thursday that the company had notified them that they will no longer have access to the company's online store as of May 22.

The move is seen as part of international sanctions on the country over its disputed nuclear program. The West has imposed banking and insurance sanctions on Iran since it suspects Iran is pursuing nuclear weapons, a charge Tehran denies.

At a Tehran shopping mall, owners of mobile phones and tablets said Thursday that they had received the message via email from the company late the night before. Retailers said they had no power over the decision.

"We have heard about it, but we are only responsible for hardware here, not software and apps," shopkeeper Bijan Ashtiani said.

In the message, Samsung said that it cannot provide access to the store, known as Samsung Apps, in Iran because of "legal barriers." It apologized to customers in emailed statement seen by the Associated Press on Thursday.

Samsung's offices in Tehran could not be immediately reached for comment due to the weekend there, and its headquarters in South Korea did not immediately respond to a request.

The decision quickly provoked ire on social media.

"Samsung is to stop its apps in Iran, oh how we appreciate our officials," wrote Bahareh, a Twitter user blaming Tehran's policy. Another, named Armin, pointed at the technology giant itself, saying: "Now, Samsung's sanctions honor us as well!"

Samsung spokesman Chris Jung in Seoul declined to comment.

Unlike Apple, Microsoft and Adobe, Samsung has provided localized services to Iranians in their native Persian language. In 2012, Finnish communications giant Nokia stopped its services in the country.

Source: http://news.yahoo.com/samsung-block-access-app-store-iran-120700300--finance.html

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Burger King 1Q earnings soar, revenue shrinks

Burger King's first-quarter earnings more than doubled even though revenue fell, as the fast-food chain trimmed several restaurant-related expenses.

The Miami-based company had warned earlier this month that sales at established restaurants were expected to fall during the quarter, and they wound up declining 1.4 percent. That includes a 3 percent drop in the United States and Canada.

Burger King said competition and a strong first quarter last year hurt U.S. and Canadian sales comparisons to this year's quarter. But it said sales from those countries rallied in March due in part to promotions like the $1.29 Whopper Jr.

The company has been adjusting its strategy to focus on more menu deals like that. McDonald's has been particularly aggressive in touting its Dollar Menu to boost traffic at a time when the restaurant industry is barely growing. Wendy's also revamped its value menu recently.

Overall, Burger King Worldwide Inc. said Friday its net income rose to $35.8 million, or 10 cents per share, in the quarter that ended March 31. That's up from $14.3 million, or 4 cents per share, in the previous year's quarter when it was still private.

The company previously said adjusted earnings, which don't count certain one-time expenses, totaled 17 cents per share in the most recent quarter.

Revenue fell about 42 percent to $327.7 million. Analysts expected $305.8 million, according to FactSet.

Total restaurant expenses, which include things like food costs and payroll expenses, fell nearly 70 percent in the quarter to $108.1 million.

Burger King has been undergoing a revamp since it was purchased and taken private in 2010 by 3G Capital, a private investment firm run by Brazilian billionaires. The company has been selling more restaurants to franchisees, a move that lowers overhead costs. Instead of booking sales from those restaurants, that means Burger King would collect franchise fees instead.

In the first quarter, the company's restaurant revenues tumbled 69 percent to $121.1 million, but its franchise and property revenues rose 19 percent to $206.6 million. The company sold 33 company-owned restaurants in the U.S. and Canada to franchisees during the quarter for $9.3 million.

Burger King said about 97 percent of its restaurants are owned and operated by independent franchisees.

The company's selling, general and administrative expenses also fell about 30 percent to $66.7 million in the quarter.

3G Capital also has slashed costs, signed international expansion deals and changed the U.S. menu to appeal to a wider audience. The moves came ahead of the company's return to public trading on the New York Stock Exchange last June.

Burger King says its efforts to revamp the brand remain on track. But CEO Bernardo Hees, a 3G partner, is moving on later this year to head Heinz, another 3G investment. Chief Financial Officer Daniel Schwartz, also a 3G partner, will succeed Lees as CEO at Burger King.

Burger King shares rose 24 cents, or 1.3 percent, to $18.30 in midday trading. They have traded between $12.91 and $20.20 since relisting.

Source: http://news.yahoo.com/burger-king-1q-earnings-soar-revenue-shrinks-122545739.html

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Ella Fitzgerald: A legacy kept alive in theater

Google celebrates the birthday of Ella Fitzgerald, the acclaimed African American singer. The Ella Fitzgerald Theater in her hometown of Newport News, Va., has worked to embody her legacy in their training programs and performances.

By Steph Solis / April 25, 2013

Today Google celebrates Ella Fitzgerald's birthday. She would have been 96.

Google

Enlarge

When the Fitzgeralds lived in Newport News, Va., the building at 2410 Wickham Ave. was the all-white Walter Reed School. Temperance Fitzgerald would walk past it every day on her way to work as a maid.

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It would never occur to her that the institution two blocks from their home would one day have her daughter?s name engraved at the entrance. But 96 years later, the Ella Fitzgerald Theater?stands as a tribute to her child's achievements as a world-renowned artist.

While Google users all over the United States observe what would have been Ella Fitzgerald's 96th birthday, the Ella Fitzgerald Theater within the Downing-Gross Cultural Arts Center in Newport News celebrates her legacy through its programs, the upcoming Ella Fitzgerald Music Festival, and an upcoming tribute ensemble.

Newport News, where Ella Fitzgerald was born in 1917, radiates with her spirit.?Michelle Gilliam, director of the Downing-Gross Cultural Arts Center and one of the founders of the annual Ella Fitzgerald Music Festival, led the restoration of the historic building that used to be the Walter Reed School to establish the Ella Fitzgerald Theater. She opened the 276-seat venue in 2008.

The theater offers a space for local artists, especially young people, to refine their talents and perform. Ms. Gilliam and Kay Sumner, executive director of the arts center, imbue Ella Fitzgerald?s spirit in their work. They train the children who participate in their programs to learn multiple art forms, as Ella Fitzgerald had, and to not let their circumstances stop them from striving for success.

"One of Ms. Fitzgerald's main concerns was youth and just the condition in which youth grow up," says Kay Sumner, executive director of the center. "We're very mindful of that with the programming that we do here. We reach out to the community youth, and we make sure that we give them constructive choices for expression.?

Ella Fitzgerald struggled throughout her childhood, having become an orphan by her early teens. Her parents separated a month after she was born. She lived with her mother, and moved with her to Yonkers, N.Y., when she was young. But when she was 15 her mother died in a car accident.

She moved in with her aunt after her mother?s death. As a form of escape, Ella Fitzgerald started skipping school and heading to movie houses. It was her love of the arts that would lead her into the streets to pursue her dream and inspire her to perform at the Apollo Theater?s ?Amateur Night.?

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/Tphnug5TODM/Ella-Fitzgerald-A-legacy-kept-alive-in-theater

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Dutch schools color orange for new king

(Ends first round) NEW YORK, April 25 (Reuters) - Selections in the first roundof the 2013 NFL Draft at Radio City Music Hall on Thursday (picknumber, NFL team, player, position, college): 1-Kansas City, Eric Fisher, offensive tackle, Central Michigan 2-Jacksonville, Luke Joeckel, offensive tackle, Texas A&M 3-Miami (from Oakland), Dion Jordan, defensive tackle, Oregon 4-Philadelphia, Lane Johnson, offensive tackle, Oklahoma 5-Detroit, Ezekiel Ansah, defensive end, Brigham Young 6-Cleveland, Barkevious Mingo, linebacker, LSU 7-Arizona, Jonathan Cooper, guard, North Carolina 8-St. ...

Source: http://news.yahoo.com/dutch-schools-color-orange-king-085650678.html

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Friday, April 26, 2013

Hitler's food taster tells of poisoning fears

BERLIN (AP) ? They were feasts of sublime asparagus ? laced with fear. And for more than half a century, Margot Woelk kept her secret hidden from the world, even from her husband. Then, a few months after her 95th birthday, she revealed the truth about her wartime role: Adolf Hitler's food taster.

Woelk, then in her mid-twenties, spent two and a half years as one of 15 young women who sampled Hitler's food to make sure it wasn't poisoned before it was served to the Nazi leader in his "Wolf's Lair," the heavily guarded command center in what is now Poland, where he spent much of his time in the final years of World War II.

"He was a vegetarian. He never ate any meat during the entire time I was there," Woelk said of the Nazi leader. "And Hitler was so paranoid that the British would poison him ? that's why he had 15 girls taste the food before he ate it himself."

With many Germans contending with food shortages and a bland diet as the war dragged on, sampling Hitler's food had its advantages.

"The food was delicious, only the best vegetables, asparagus, bell peppers, everything you can imagine. And always with a side of rice or pasta," she recalled. "But this constant fear ? we knew of all those poisoning rumors and could never enjoy the food. Every day we feared it was going to be our last meal."

The petite widow's story is a tale of the horror, pain and dislocation endured by people of all sides who survived World War II.

Only now in the sunset of her life has she been willing to relate her experiences, which she had buried because of shame and the fear of prosecution for having worked with the Nazis, although she insists she was never a party member. She told her story as she flipped through a photo album with pictures of her as a young woman, in the same Berlin apartment where she was born in 1917.

Woelk first revealed her secret to a local Berlin reporter a few months ago. Since then interest in her life story has been overwhelming. School teachers wrote and asked her for photos and autographs to bring history alive for their students. Several researchers from a museum visited to ask for details about her life as Hitler's taster.

Woelk says her association with Hitler began after she fled Berlin to escape Allied air attacks. With her husband gone and serving in the German army, she moved in with relatives about 435 miles (700 kilometers) to the east in Rastenburg, then part of Germany; now it is Ketrzyn, in what became Poland after the war.

There she was drafted into civilian service and assigned for the next two and a half years as a food taster and kitchen bookkeeper at the Wolf's Lair complex, located a few miles (kilometers) outside the town. Hitler was secretive, even in the relative safety of his headquarters, that she never saw him in person ? only his German shepherd Blondie and his SS guards, who chatted with the women.

Hitler's security fears were not unfounded. On July 20, 1944, a trusted colonel detonated a bomb in the Wolf's Lair in an attempt to kill Hitler. He survived, but nearly 5,000 people were executed following the assassination attempt, including the bomber.

"We were sitting on wooden benches when we heard and felt an incredible big bang," she said of the 1944 bombing. "We fell off the benches, and I heard someone shouting 'Hitler is dead!' But he wasn't. "

Following the blast, tension rose around the headquarters. Woelk said the Nazis ordered her to leave her relatives' home and move into an abandoned school closer to the compound.

With the Soviet army on the offensive and the war going badly for Germany, one of her SS friends advised her to leave the Wolf's Lair.

She said she returned by train to Berlin and went into hiding.

Woelk said the other women on the food tasting team decided to remain in Rastenburg since their families were all there and it was their home.

"Later, I found out that the Russians shot all of the 14 other girls," she said. It was after Soviet troops overran the headquarters in January 1945.

When she returned to Berlin, she found a city facing complete destruction. Round-the-clock bombing by U.S. and British planes was grinding the city center to rubble. ??

On April 20, 1945, Soviet artillery began shelling the outskirts of Berlin and ground forces pushed through toward the heart of the capital against strong resistance by die-hard SS and Hitler Youth fighters.

After about two weeks of heavy fighting, the city surrendered on May 2 ? after Hitler, who had abandoned the Wolf's Lair about five months before, had committed suicide. His successor surrendered a week later, ending the war in Europe.

For many Berlin civilians ? their homes destroyed, family members missing or dead and food almost gone ? the horror did not end with capitulation.

"The Russians then came to Berlin and got me, too," Woelk said. "They took me to a doctor's apartment and raped me for 14 consecutive days. That's why I could never have children. They destroyed everything."

Like millions of Germans and other Europeans, Woelk began rebuilding her life and trying to forget as best she could her bitter memories and the shame of her association with a criminal regime that had destroyed much of Europe.

She worked in a variety of jobs, mostly as a secretary or administrative assistant. Her husband returned from the war but died 23 years ago, she said.

With the frailty of advanced age and the lack of an elevator in her building, she has not left her apartment for the past eight years. Nurses visit several times a day, and a niece stops by frequently, she said.

Now at the end of her life, she feels the need to purge the memories by talking about her story.

"For decades, I tried to shake off those memories," she said. "But they always came back to haunt me at night." ??

Source: http://news.yahoo.com/hitlers-food-taster-tells-poisoning-fears-150032362.html

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This Laser Shutter Photography Rig Freezes Insects In Flight

Lacking the technical skills needed to build his own sophisticated shutter trigger system from scratch, photographer Linden Gledhill hacked together a rig of his own using an off-the-shelf system called StopShot so he could snap macro shots of insects in flight. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/wYliecDTjU4/this-laser-shutter-photography-rig-freezes-insects-in-flight

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Business Financial Services, Inc. Announces New $82 Million Credit ...

Specialty Finance Leader Provides Working Capital to Underserved Small Businesses

CORAL SPRINGS, FL ? Business Financial Services, Inc. (BFS), a leading specialty finance company since 2002, announced a new $82 million credit facility provided by Wells Fargo Capital Finance, part of Wells Fargo & Company (NYSE: WFC). The new credit line, which replaces a smaller facility with another lender, bolsters the Company?s ability to serve the owners of small and medium-size businesses throughout the United States, and through affiliates in Canada and the United Kingdom.

?Business Financial Services has grown rapidly over the last 11 years by effectively serving business owners whose working capital needs are not met by traditional funding sources,? said Marc Glazer, CEO and co-founder of the Company. ?This new credit line will enable us to help even more businesses address their ongoing needs and take advantage of real opportunities. With quick funding of loans as small as $4,000 and as large as $2,000,000 that are structured to meet the needs of the borrower, we help fill a critical credit gap in the economy.?

View a video of Marc Glazer discussing small business financing solutions from Business Financial Services.

About Business Financial Services

Business Financial Services, Inc. is a leading specialty finance company providing short term loans and cash advances to owners of small and medium-size businesses. Founded in 2002 with headquarters in South Florida and supported by private equity and institutional partners, BFS serves businesses in all 50 states and Puerto Rico, and through affiliates, in Canada and the United Kingdom. BFS is proud to be an accredited BBB company with an A+ rating. Visit the BFS website at www.businessfinancialservices.com.

About Wells Fargo Capital Finance

Wells Fargo Capital Finance is the trade name for certain asset-based lending, accounts receivable and purchase order finance services of Wells Fargo & Company and its subsidiaries, and provides traditional asset-based lending, specialized senior secured financing, accounts receivable financing and purchase order financing to companies across the United States and Canada. Dedicated teams within Wells Fargo Capital Finance provide financing solutions for companies in specific industries such as retail, software publishing and high-technology, commercial finance, staffing, government contracting, timeshare development and others. For more information, visit wellsfargocapitalfinance.com

Contacts:

For Business Financial Services, Inc.
Fahlgren Mortine
Patrick Gallagher
(216) 298-4617
pat.gallagher@fahlgren.com

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Source: http://www.franchising.com/news/20130424_business_financial_services_inc_announces_new_82_m.html

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Thursday, April 25, 2013

RightAnswer Joins Society of Chemical Manufacturers and Affiliates ...

04/22/2013 (press release: Inbound Marketing PR) // Denver, Colorado, USA // Glen Markham

RightAnswer just announced their new alliance with SOCMA (Society of Chemical Manufacturers and Affiliates), which will help the organization strengthen ties within the EHS community. SOCMA represents a variety of chemical companies that produce and distribute commercial and consumer products; through this union, RightAnswer will be able to offer its in-depth chemical and regulatory information to more personnel within the batch, custom, and specialty chemical industry, including access to its comprehensive Knowledge Solutions.

SOCMA plans to provide RightAnswer and other new members a wealth of information that will help their businesses succeed. From advocacy to networking and regulatory support, the Society will leverage its members to gain visibility in and benefit from the vast network of SOCMA alliances within the environmental, health and safety industries.

RightAnswer sees this as a networking opportunity that will bring increased exposure to its products and services. ?Through our new partnership with SOCMA, more attention and visibility can be brought to our Knowledge Solutions, a product that provides EHS experts with up-to-date and accurate chemical, MSDS, reproductive risk, and regulatory compliance information,? said Glen Markham, at RightAnswer. With more publicity and attention garnered through the RightAnswer and SOCMA partnership, a larger audience can gain access to and benefit from the comprehensive chemical data (over 400,000 substances) that RightAnswer provides.

About RightAnswer

Founded in 1996 by chemical industry experts, RightAnswer.com began as a custom software development and consulting firm. Today, they are a leader in online regulatory compliance systems serving Environment, Health, and Safety (EHS) markets all over the world. As an industry leader in Internet-based Software-as-a-Service, RightAnswer delivers reliable data solutions and cost-effective document systems to help customers meet Environment, Health, and Safety (EHS) requirements. RightAnswer continuously analyzes processes, methodology, procedures and standards to ensure the usability and quality of its products..

About SOCMA

SOCMA, the Society of Chemical Manufacturers and Affiliates, Inc., is the only U.S. based trade association dedicated solely to the batch, custom and specialty chemical industry. SOCMA plays an indispensable role in the global chemical industry by producing intermediates, specialty chemicals and ingredients used to develop a wide range of commercial and consumer products. These products are essential to the life, health and well-being of people everywhere. SOCMA supports the industry with programs that maximize commercial and networking opportunities, increase public confidence and influence the passage of rational laws and regulations.

Social Media Tags:Chemical Manufacturers and Affiliates, SOCMA, business alliance, chemical companies

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Source: http://www.wirednewsengine.com/2013/04/24/rightanswer-joins-society-of-chemical-manufacturers-and-affiliates-socma_2013042425971.html

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Wednesday, April 24, 2013

'Toggle switch' to burn fat identified

Apr. 23, 2013 ? For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning.

The results are now being presented in the journal Nature Communications.

Many people not only in industrialized nations struggle with excess weight -- but all fat is not alike. "Love handles" in particular contain troublesome white fat cells which store excess food. Brown fat cells are the exact opposite: they burn excess energy as the desirable "heaters" of the body. Scientists at the University of Bonn working with Prof. Dr. Alexander Pfeifer, Director of the Institute for Pharmacology and Toxicology, have spent years using animal models to explore how the undesirable white fat can be converted into sought-after brown fat. "In this way, excess pounds may be able to simply be melted away and obesity combated," says Prof. Pfeifer.

A kind of "trigger switch" spurs fat burning

The researchers have now decoded a "microRNA switch" in mice which is important for brown fat cells. Micro-RNAs are located in the genome of cells and very quickly and efficiently regulate gene activity. The researchers studied a specific microRNA: microRNA 155. The gene regulator micro-RNA 155 inhibits a certain transcription factor, that controls brown fat cell function. Surprisingly, Prof. Pfeifer and his team found that the transcription factor also regulates the levels microRNA 155 establishing a tight feed-back loop that works like a toggle switch: When the microRNA is highly expressed brown fat cell differentiation is blocked; conversely, if the transcription factor wins the upper hand, brown fat is produced at an increased level and this in turn boosts fat burning in the body.

In knockout mice, the gene for Micro-RNA 155 was silent

The researchers at Bonn University and their colleagues from the Federal Institute of Drugs and Medical Devices (BfArM) and from the University of Regensburg worked with so-called transgenic and knockout mice in whom the gene for micro-RNA 155 was either increased or silenced. "The mechanism was already set in motion when the micro-RNA 155 was only halved in the mice," reports lead author Yong Chen, graduate student of the NRW International Graduate School BIOTECH-PHARMA. The mice then had significantly more brown fat cells available than did the control gro up -- and had even converted white fat cells into brown fat cells.

Clues to the causes of lipid metabolism diseases

The micro-RNA functions as an antagonist to the brown fat cells. "As long as enough micro-RNA 155 is present, the production of brown fat cells is blocked," says Chen. Only if it falls below a certain proportion does this brake let up; the blueprint for brown fat can be read and implemented by the cell -- the desired fat burners can develop. These findings help scientists better understand the causes of lipid metabolism diseases.

Hope for new therapies against obesity

The scientists at the University of Bonn see in their results a potential starting point for drugs to combat obesity. The researchers have clues to the fact that the results, if anything, can be transferred from mice to humans. Thus, for example, researchers in Leipzig found increased levels of micro-RNA 155 in significantly overweight patients. This corresponds to findings from animal models: A lot of micro-RNA 155 is associated with reduced fat burning. "However, we are still in the basic research stage," says Prof. Pfeifer. The path to suitable drugs is still a long one.

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The above story is reprinted from materials provided by Universit?t Bonn, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Yong Chen, Franziska Siegel, Stefanie Kipschull, Bodo Haas, Holger Fr?hlich, Gunter Meister, Alexander Pfeifer. miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nature Communications, 2013; 4: 1769 DOI: 10.1038/ncomms2742

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/2asP3gl0lPk/130423110742.htm

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Microwave imaging can see how well treatment is progressing

Apr. 24, 2013 ? Microwave imaging can be used to monitor how well treatment for breast cancer is working, finds new research published in BioMed Central's open access journal Breast Cancer Research. Microwave tomography was able to distinguish between breast cancer, benign growths, and normal tissue.

Eight women with breast cancer were treated with chemotherapy until surgery, as part of their normal therapy. During treatment, magnetic resonance image was supplemented with microwave tomography at the Dartmouth-Hitchcock Medical Center. Regions of high conductivity corresponded to the tumors, low conductivity to normal tissues, and unlike other imaging techniques, body mass index (indicating the amount of body fat), age or breast density did not appear to affect the results.

This imaging technique is low cost and can be repeated at numerous stages during treatment. Paul Meaney from Dartmouth College, who led the study explained, "By recalling patients for scans during their treatment we found that we could actually see tumors shrinking in women who responded to chemotherapy. Microwave tomography could therefore be used to identify women who are not responding to initial therapy and their treatment changed appropriately at an early stage."

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The above story is reprinted from materials provided by BioMed Central Limited.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Paul M Meaney, Peter A Kaufman, Lori S Muffly, Michael Click, Steven P Poplack, Wendy A Wells, Gary N Schwartz, Roberta M di Florio-Alexander, Tor D Tosteson, Zhongze Li, Shireen D Geimer, Margaret W Fanning, Tian Zhou, Neil R Epstein and Keith D Paulsen. Microwave imaging for neoadjuvant chemotherapy monitoring: initial clinical experience. Breast Cancer Research, (in press) [link]

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/OtTQU3Bwu6o/130423211830.htm

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Tuesday, April 23, 2013

TC Cribs: Inside LinkedIn, The Professional Social Network With A Surprisingly Casual HQ

linkedinIt's time for a brand spankin' new edition of Cribs, the TechCrunch TV series where we snoop around inside the parts of hot tech companies that are typically for employees only. Just like Walt Whitman, the tech industry contains multitudes, and we try to represent it all in Cribs. That means that in addition to touring smaller startups, we also like to go inside established tech giants -- and it was pretty amazing to have the chance to take an in-depth tour of LinkedIn, the professional social network that's grown from its 2002 inception in Reid Hoffman's apartment to a staff of thousands, a user base of hundreds of millions, a hugely successful initial public offering, and continued stock market success.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/n5VRmgZYDhw/

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Highly active antiretroviral therapies may be cardioprotective in HIV-infected children, teens

Apr. 22, 2013 ? Long-term use of highly active antiretroviral therapies (HAART) does not appear to be associated with impaired heart function in children and adolescents in a study that sought to determine the cardiac effects of prolonged exposure to HAART on children infected with the human immunodeficiency virus (HIV), according to a report published Online First by JAMA Pediatrics, a JAMA Network publication.

Prior to contemporary antiretroviral therapies (ARTs), children infected with HIV were more likely to have heart failure.

Steven E. Lipshultz, M.D., of the University of Miami Leonard M. Miller School of Medicine, Florida, and colleagues used statistical models to compare echocardiographic measures in the National Institutes of Health-funded Pediatric HIV/AIDS Cohort Study's Adolescent Master Protocol (AMP).

The study included 14 pediatric HIV clinics in the United States. The participants were 325 perinatally HIV-infected children receiving HAART; 189 HIV-exposed but uninfected children; and 70 HIV-infected (mostly HAART-unexposed) historical pediatric controls patients from the National Institutes of Health-funded Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2-HIV) Study.

"Our results indicate that the current use of combination ART, usually HAART, appears to be cardioprotective in HIV-infected children and adolescents. This finding is even more relevant in the developing world where the prevalence of HIV disease in children is much higher," the study notes.

Scores for left ventricular (LV) fractional shortening (a measure of cardiac function) were significantly lower among HIV-infected children from the P2C2-HIV Study than among the AMP HIV-infected group or the 189 AMP HIV-exposed but uninfected controls, the study results indicate. The results also show that for HIV-infected children, a lower nadir CD4 percentage and a higher current viral load were associated with significantly lower cardiac function.

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The above story is reprinted from materials provided by American Medical Association (AMA).

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Journal Reference:

  1. Steven E. Lipshultz et al. This study suggests that highly active ART (HAART) does not appear to impair heart function. JAMA Pediatrics, April 22, 2013 DOI: 10.1001/jamapediatrics.2013.1206

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/T_-jEq84p3o/130422175506.htm

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